2018

Sui X, Arlt H, Brock KP, Lai ZW, DiMaio F, Marks DS, Liao M, Farese RV Jr, Walther TC. Cryo-electron microscopy structure of the lipid droplet-formation protein seipin. Cell Biol. 2018 Dec 3;217(12):4080-4091. doi: 10.1083/jcb.201809067. Epub 2018 Oct 16. PMID: 30327422

Nguyen AD, Nguyen TA, Singh RK, Eberlé D, Zhang J, Abate JP, Robles A, Koliwad S, Huang EJ, Maxfield FR, Walther TC, Farese RV Jr. Progranulin in the hematopoietic compartment protects mice from atherosclerosis.   Atherosclerosis. 2018 Aug 30;277:145-154. doi: 10.1016/j.atherosclerosis.2018.08.042. [Epub ahead of print] PMID: 30212683

Jayson CBK, Arlt H, Fischer AW, Lai ZW, Farese RV Jr, Walther TC. Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells. Mol Biol Cell. 2018 Aug 15;29(17):2045-2054. doi: 10.1091/mbc.E18-05-0282. Epub 2018 Jun 27. PMID: 29949452

Nguyen AD, Nguyen TA, Zhang J, Devireddy S, Zhou P, Karydas AM, Xu X, Miller BL, Rigo F, Ferguson SM, Huang EJ, Walther TC, Farese RV Jr. Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12): E2849-E2858. doi: 10.1073/pnas.1722344115. Epub 2018 Mar 6. PMID: 29511098

Li Z, Lai ZW, Christiano R, Gazos-Lopes F, Walther TC, Farese RV Jr. Global Analyses of Selective Insulin Resistance in Hepatocytes Caused by Palmitate Lipotoxicity.V. Mol Cell Proteomics. 2018 May;17(5):836-849. doi: 10.1074/mcp.RA117.000560. Epub 2018 Feb 5.PMID: 29414761

Prévost C, Sharp ME, Kory N, Lin Q, Voth GA, Farese RV Jr., Walther TC. Mechanism and Determinants of Amphipathic Helix-Containing Protein Targeting to Lipid Droplets. Dev Cell. 2018 Jan 8;44(1):73-86.e4. doi: 10.1016/j.devcel.2017.12.011. Epub 2018 Jan 8. PubMed PMID: 29316443

Inloes JM, Kiosses WB, Wang H, Walther TC, Farese RV Jr., Cravatt BF. Functional Contribution of the Spastic Paraplegia-Related Triglyceride Hydrolase DDHD2 to the Formation and Content of Lipid Droplets. Biochemistry. 2018 Feb 6;57(5):827-838. doi: 10.1021/acs.biochem.7b01028. Epub 2017 Dec 26.
PMID: 29278326

Acosta-Alvear D, Karagöz GE, Fröhlich F, Li H, Walther TC, Walter P. The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1. Elife. 2018 Dec 24;7. pii: e43036. doi: 10.7554/eLife.43036. PMID: 30582518

Krahmer N, Najafi B, Schueder F, Quagliarini F, Steger M, Seitz S, Kasper R, Salinas F, Cox J, Uhlenhaut NH, Walther TC, Jungmann R, Zeigerer A, Borner GHH, Mann M. Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis. Dev Cell. 2018 Oct 22;47(2):205-221.e7. doi: 10.1016/j.devcel.2018.09.017. PMID: 30352176

Eikrem Ø, Walther TC, Flatberg A, Beisvag V, Strauss P, Farstad M, Beisland C, Koch E, Mueller TF, Marti HP. Fine needle aspirates of kidneys: a promising tool for RNA sequencing in native and transplanted kidneys. BMC Nephrol. 2018 Sep 5;19(1):221. doi: 10.1186/s12882-018-1012-4. PMID: 30185151

Goldberg IJ, Reue K, Abumrad NA, Bickel PE, Cohen S, Fisher EA, Galis ZS, Granneman JG, Lewandowski ED, Murphy R, Olive M, Schaffer JE, Schwartz-Longacre L, Shulman GI, Walther TC, Chen J. Deciphering the Role of Lipid Droplets in Cardiovascular Disease: A Report From the 2017 National Heart, Lung, and Blood Institute Workshop. Circulation. 2018 Jul 17;138(3):305-315.doi:10.1161/CIRCULATIONAHA.118.033704. Review. PMID: 30012703