2020

Christiano R, Arlt H, Kabatnik S, Mejhert N, Lai ZW, Farese RV Jr, Walther TC. A Systematic Protein Turnover Map for Decoding Protein Degradation. Cell Rep. 2020 Nov 10;33(6):108378. doi: 10.1016/j.celrep.2020.108378.PMID: 33176155 

Chitraju C, Fischer AW, Farese RV Jr, Walther TC. Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.Cell Rep. 2020 Nov 3;33(5):108348. doi: 10.1016/j.celrep.2020.108348.PMID: 3314746

Becuwe M, Bond LM, Pinto AFM, Boland S, Mejhert N, Elliott SD, Cicconet M, Graham MM, Liu XN, Ilkayeva O, Saghatelian A, Walther TC, Farese RV. FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis. J Cell Biol. 2020 Oct 5;219(10). doi: 10.1083/jcb.202006111. PubMed PMID: 32915949.

Olarte MJ, Kim S, Sharp ME, Swanson JMJ, Farese RV Jr, Walther TC. Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting. Dev Cell. 2020 Aug 24;54(4):471-487.e7. doi: 10.1016/j.devcel.2020.07.001. Epub 2020 Jul 29. PubMed PMID: 32730754; NIHMSID:NIHMS1617288.

Sui X, Wang K, Gluchowski NL, Elliott SD, Liao M, Walther TC, Farese RV Jr. Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme.Nature. 2020 May;581(7808):323-328. doi: 10.1038/s41586-020-2289-6. Epub 2020 May 13. PMID: 32433611

Petit CS, Lee JJ, Boland S, Swarup S, Christiano R, Lai ZW, Mejhert N, Elliott SD, McFall D, Haque S, Huang EJ, Bronson RT, Harper JW, Farese RV Jr, Walther TC. Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant wobbler mice, a model of motor neuron degeneration. Natl Acad Sci U S A. 2020 May 12;117(19):10565-10574. doi: 10.1073/pnas.1913956117. Epub 2020 Apr 28. PMID: 32345721


Mejhert N, Kuruvilla L, Gabriel KR, Elliott SD, Guie MA, Wang H, Lai ZW, Lane EA, Christiano R, Danial NN, Farese RV Jr, Walther TC. Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression. Mol Cell. 2020 Mar 19;77(6):1251-1264.e9. doi: 10.1016/j.molcel.2020.01.014. Epub 2020 Feb 4. PubMed PMID: 32023484.